Questions in Gas Chromatography (GC)
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Why You Should Use Volatile Buffers in LC-M?
Choosing the right buffers and solvents is critical in LC-MS because the entire mobile phase directly enters the mass spectrometer. Compatibility with...
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Gas Chromatography (GC) is a powerful analytical technique, How It Works?
Gas Chromatography (GC) is a powerful analytical technique widely used to separate and analyze volatile organic compounds across a variety of sample t...
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100% level impurity calculation in gc
Suppose this in residual sample method Method -1 Here, methanol specification =NMT 1000 ppm Standard concentration=0.1 mg/ml Sample concentration=100...
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Peak area variability in DMSO analysis
Hello, I am running an impurity analysis method for DMSO with the following parameters: FID Temperature: 250 °C Injector Temperature: 250 °C Column...
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Unexpected Peaks After Running a Solvent Blank
I was running a sequence of product samples and decided to inject a methanol blank in between. To my surprise, I saw unexpected peaks—some of which ...
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Retention Time Shifts Mid-Run
In a long GC run (about 30 samples), I noticed that retention times started shifting gradually. Early samples were fine, but later ones drifted....