100% level impurity calculation in gc
Suppose this in residual sample method
Method -1
Here, methanol specification =NMT 1000 ppm
Standard concentration=0.1 mg/ml
Sample concentration=100 mg/ml
Calculation for 100% metlanol respect to sample=(0.1*1000000)/100=1000 ppm
Method:2
Specification methanol= NMT 1000 ppm
=1000 mg/L=0.1%
Sample concentration=100 mg/ml
Calculation methanol 100% respect to sample =100 mg/ml0.1%=(100*0.1)/100=0.1mg/ml=100 ppm
Why 10 time difference between two methods?
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1
1000 ppm for methanol in sample not the concentration of the std so the concentration of the std depends on the concentration of the test method one correct method 2 is in correct
