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Sustainability in the lab is no longer just a buzzword—in 2025, it’s a necessity. With rising solvent costs and stricter waste regulations, Green Chromatography is becoming the new gold standard in pharmaceutical R&D and QC.

3 Trends defining the Green Shift:

Solvent Swaps: We are seeing successful validations replacing traditional solvents like Acetonitrile and Methanol with greener, bio-renewable alternatives like Ethanol and Dimethyl Carbonate (DMC).

Miniaturization: The shift to micro-LC and nano-LC is cutting solvent consumption by up to 90% without sacrificing resolution.

Core-Shell Efficiency: Using sub-2 µm core-shell particles to speed up runs and drastically reduce mobile phase usage.

It’s not just about saving the planet; it’s about saving the budget.

Call to Action: What’s the biggest challenge you face in making your methods greener? Let's discuss in the comments. ?

#GreenChemistry #HPLC #Sustainability #Laboratory #PharmaRD #GreenHPLC #AnalyticalChemistry #2025Trends

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