During a gradient HPLC run, you notice a steady increase in baseline noise and a drifting UV baseline. What is the MOST probable cause? Poll

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Detector cell fouling
58.3% 14 votes
Mobile phase mismatch between A and B solvents
25% 6 votes
Column contamination
16.7% 4 votes
Faulty autosampler seal
0% 0 votes
gradient hplc HPLC
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youhana Hosny Author
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