Why is my peak tailing in the chromatogram?
My peak shows tailing how can I solve it?
3 Answers
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Use end-capped or well-deactivated columns.
Optimize pH, especially for ionizable analytes.
Add modifiers (e.g., TEA) to reduce interactions.
Inject smaller sample volumes.
Replace or regenerate the column if damaged.
Optimize pH, especially for ionizable analytes.
Add modifiers (e.g., TEA) to reduce interactions.
Inject smaller sample volumes.
Replace or regenerate the column if damaged.
0
good answers thanks :)
-1
how can I calulate tailing factor
