HPLC Column Volume Calculation

Need to quickly calculate void volume, void time, or k′ (K prime)? ?
Our HPLC Calculator app now includes an easy-to-use tool for estimating these key parameters in seconds!

Just enter:

Column length (cm)

Internal diameter (mm)

Flow rate (mL/min)

Peak retention time (min)

% Porosity (? Tip: use 70% as default if unsure)

Tap Calculate to get:

✅ Void Volume (mL)

✅ Void Time (min)

✅ K′ value (retention factor)

Whether you're in the lab or validating a method, this tool helps streamline your workflow and eliminate manual math.

Try it now and simplify your HPLC calculations!